Hi, it's not every day that you have a Nobel Laureate here in the lab. very Marshall Thank you for joining us hey young Dave Yes Raja is making me cry Anyway, the Berry is a not only a total electronics node and hobbyist and vintage HP nut as well as a vintage tech not we've been talking all about Tektronix our scopes and HP gear and all sorts of stuff. but you're right I mean we could talk about that well like cows come home I do all the medical things so I end up being infectious disease specialists and a gastroenterologist because I discovered that germ in the stomach which causes ulcers just called the Helicobacter Pylori because on tyke and its initials are HP Oh so it annoys me I could never get the website Hp.com because please this American company some some this upstart company beat you to it. Yeah so I thought I'd come to teach you Dave a bit about human health.

You know that the stomach because I know you electronics engineers. You got nothing. You know nothing about flesh nothing. So you won the 2005 yeah, 2005 Nobel Prize for Medicine for Medicine and my partner there was Dr..

Robin Warren is a pathologist right? and he had been looking for cancer and stomach biopsies and he saw these bacteria and although he had seen the bacteria and a few people like about 20 people, he didn't know how they could survive in the stomach. it's not a lot of acid in a glass bacteria and he didn't know whether these bacteria were causing any kind of disease. So I turned along and turned up one day looking for a research project. Right like impromptu, He told me all about them and I said well, what is really interesting? how could bacteria be living in the stomach? Yes, and they've never been reported in the medical book.

so all the medical books say bacteria cannot live in acid. Got it? So yeah, what a great interesting research that would be fantastic. And so off we went. And so that started off in 1981 and no, the next two or three years we worked out.

but they, these bacteria cost fantastic. No, not stress, not stress. There you go folks, the Nobel Laureate says else instead I'm not caused by stress. Yes, so that was the prevailing theory firm for a hundred years of war.

And because what? I found out this is secret secret stuff your doctor will never tell you when he or she doesn't know what's wrong with you, they'll blame it on stress. So if ever they say Dave this is girls by stress I mean cheap jobs? Too stressful. That really means right? We don't know what's wrong with you. but but but actually, it probably also means that I ran a bunch of tests on you and everything came up normal.

So in other words you might say, well, you haven't really got a diagnosis. However, you've got a diagnosis that nothing bad is going on And that is good because that means probably you're gonna get better and it's probably the virus or something. However, you know people with ulcers used to have it all their life. They vomited blood.

They could die from it. What a famous people had it any. When we studied these bacteria a bit more, we found out that more than half the people in the world Wow we're infected and still are. So in Australia.

In fact, that's been decreasing and it's hard to find people with ulcers nowadays. It used to be very common go like in your parents generation, my parents and nowadays probably about 20 percent probably 10 percent of Australian is still have it. Anybody who's migrated from a developing country like the Middle East Asia China Africa South America that more than half the population in those countries have still got it. Wow and they still get a lot of ulcers and in China they get a lot of stomach cancer.

So the problem is if you have a germ irritating your body for your whole life because you catch it when you're two or three years old from right from your mother and then you know after 30 or 40 or 50 years you know it can lead to some other things. But anyway, that's enough medicine. Oh you're talking about pepto-bismol So anyway, one of the Dave and I were talking about how we should have recorded the whole conversation before. It was fascinating.

Yeah, in families you have a couple of beers. One thank you. We do it properly. Is there any better? So we're talking about when I was a kid we used to live in the rubbish tip in the shoebox I knew a safe.

my god you guys had a shoebox. It was one of those kinds of conversations but my and the elections coming out of course right of course. and so after Bob Hawke came in you know they floated the Australian count the currency they did I was a penniless hobbyist. yeah was doctor luckily.

but you know with the family everything I would still had no dough and the Australian interest rate went up to 16. Yeah! I Remember that? yeah it was very very painful and so you know God So I was doing my research and one of the reasons and people didn't believe it was important was because so many people had it must be just a canvas right? So that was one thing. but one of the things that I discovered was there's this medicine around the world called Pepto-bismol now in America and the best one was Tom Cruise in that movie Rain Man Rain Man you know he's trying to sell those Corvettes yep and he can't sell them there on the it locked up in the Harvard quarantine or something and you seem go to the company drinks this pink medicine well I found out this stuff pepto-bismol was that was selling buckets of it in America and a lot of other countries England and it can. The thing that was in it, they thought it was some kind of an tested which coated the stomach because people used to take it and they sell it in the Superman and they'd feel better.

It kind of work. So the people who couldn't afford to have health insurance or anything right would they talk to their mates. they'd say oh yeah oh yeah, go down this the supermarket the far more and get some pepto-bismol in and just I just chug along it. Yes, people in America were taking the stuff and I worked out.

but it contained bismuth which are heavy metal. Yeah, that's in the same column of the table of our as arsenic phosphorus may be. You know all down that Con: the heaviest metal nonreactive element actually is bismuth. so you know arsenic was used to treat syphilis, right? Hey, Mercury? Yeah.

Oh treating syphilis and peepees to get a black line on their teeth. You know all those old Victorian guys. So before we had antibiotics, people knew or some people knew that you could take heavy metals and we would dose you with it until you just died. at which point we'd stop right and you could be cured of you syphilis.

So all the rich kings and princes and everything they had these black lines around their gums from the heavy metals. No. I remembered the bismuth killed bacteria and so I tested it on our stomach bacteria and lo and behold Oh killed Okay so you guess that there was stomach. there was bacteria in the stomach even though everyone said yes.

So Dr.. Warren oh I we knew they were there. Oh we could. we could go sample people and we could.

We grew them in the lab and tasted antibiotics and everything. But the the thing that rocketed me off if you like into a bit of an interesting career was I discovered that this over-the-counter medicine in America called Pepto-bismol they sell hundreds of millions of dollars of it was actually killing the bacteria. So the people in the community who were taking this stuff and had it in their bathroom cupboard we're chronically infected with the bacteria. Yeah I know I thought and I found that if you add a simple antibiotic to you and kill about, say over Santa Clara and in two weeks you cure lots of people permanently.

So if you get rid of the germs right you're else is just totally cured. right in the story. So with the sixteen percent interest on my mortgage, I was lucky to license a patent to his company in the US and they said Barry we need to tell America about this because there's a lot of dough and it could be else a treatment. yeah and so I I then had research funding at the University of Virginia There was a nice guy There called Richard McKellen from Brisbane but he was professor.

they hired me over and so for five years we did the research funding and after that I on this thing we've got lots of publicity and it took about 10 years to convince. Oh and then we have to figure out a good treatment. so we got a good treatment. We got some medical tests.

So nowadays if you go to your GP you say my dad used to have ulcers now I think I'm getting one right. Story like that he would you might do a blood test on you but probably don't do a breath test Oh which is a killing. You can detect it from the breath well you have to. You have to take an isotope with urea in it which is split and urea is just ammonia and carbon dioxide joined together right? It's a waste product in your body zone.

Yes, yeah but it's in your stomach, fluids and survivor and the germs Flitz that into Co2 and ammonia and the Co2 that then comes out in your breath in about 10 minutes. So so one of the things so that I eventually did was embed that test. and so nowadays all over Australia any not allowed your GP goes. You go down the lap, you swallow this capsule, wait 10 minutes, blow up a balloon, send it off to the lab, then they see Whoa! you've got your score of 3,000 right? And then the beautiful thing is when you take the the antibiotic treatment a month later they check you again.

It's like you've never got a score of three. So you go from this mega level down to practically zero on this isotope test. and there's a secure and you didn't have to have a scope down and you didn't have to worry about the fact that you were hopeless and under stress and everything. You're still that.

but your ulcer is going. said no. Is this stool that myth that stress causes ulcers on the way? so it's so persistently. it kind of is.

And but it part of it. is this lying. This this this con job that doctors have and I don't know we did. We get this on tape before that so whenever your doctor can't figure out what's wrong with, he says caused by stress.

So so kids I might give a talk to say high school students and they say Oh Orson Uni students I don't know. Is there anything that we could do to help you to win a Nobel Prize and I say well next time you go to the doctor and he says something's caused by stress, you think if I could find a real cause I probably with my noble prize according to Barry - you're resting Wow So what can you think of that scores boisterous I'll give you Oh YouTube Burnouts caused by stress but headaches right? Like usually if you got a headache I'd say 90% of the time it's gonna be postural. You're sitting in fried s cuz I got pedaling around and you sort of tracing some horrible little sandal across a instrument or something. you know.

and and it's so interesting. you do so stress or posture what we say stress, but it's usually posture or something like that right? in people. Some people get migraines I used to get them grew out of it I'm not intelligent enough anymore, but musi smile if people get migraines I've never in my life so obviously I'm so so like headaches. No one in any individual we might have this kind of a diagnosis.

We can't kill you because we don't really understand the fundamental cause of a headache. Where's it come from? interesting chemical in your blood or is it on muscles and so if it be a really miracle Bakken There's a chapter on something of 100 pages in the chapter and they have 20 causes of something. Yeah, that means they didn't really know the real cause right? So with ulcers that used to have a hundred and fourteen pages in the medical world really and there would be a list of about 20 causes of how duodenal know of stomach ulcers Wow well why is it 94? Well, 90% of them around the world would be the germ right? and the other 10% people take aspirin or arthritis medicine Oh like that and it's not alcohol so I always try. Marshall Can whiskey cause ulcers I say it no no it's good.

actually does poison the bacteria or a little bit right? I cannot help So the things that so I'm the hobbyist yes you are Then I was telling you that I started building us 100 computers after doing some actually I got a scholarship to do electronic engineering yeah of high school but also but decided that do medicine and do electronics as a hobby. rise in the 1970s 19 1968 when I did my 1969 actually 50 years ago this year many men on the moon? Yes absolutely. So that was my first year in Uni and I got a scholarship I can't remember how I got a scholarship. Maybe I didn't have one and I said right but you know electronics in those days were so expensive a transistor would cause sages, you know and so I thought if I'm a doctor I have no money.

no electronics is a hobby so that's great. That is brilliant and so I did I did some night school of circuit theory and then I did a summer school of microcontrollers I was like the Intel oh my god you are sitting here between is my first computer day that is your first computer cost me $350 and apparently I outbid him on this. you were we were both bidding I had no idea I was bidding against a Nobel laureate for the I think I'm sorry now after after we finished this, I'm going to kill you as still as long as you publish the content. that's all right.

you're mine. Dave's gonna do a video on that for me? Yeah, but shall we assemble it? Should I assemble it? look I see it. it's new in box smells but it's that cardboard II smell again but it's like a shrink. Anyway, it was so beautiful and my poor wife I mean she was the children were starving for but then I might wanted to control his sprinklers.

the wall used to run dry all the time, right? so he said I need Barry I need my sprinklers to be smart so they cycled through. When they run out of water, they stop until the world charges up again and then they'll start up again Where they left off. not at the beginning. So I built a sprinkler control on machine coded it.

nice real-time claw. No no, it's no compiler for this that that's right, it was I had a clock. yeah and the sprinkler controller written in machine code in 2k Iran was not. There's a lot Friday but that's a lot for sprinkler controller.

it meant here. a bit loosey-goosey with you code. Anyway, so he was heading with you and he paid me mighty pen $250 or something. I then put that into an S 100 computer.

Yeah, so I was only one of two doctors at Robert hospitals knew what a computer was. The other bloke in when he was a surgeon name was Bill and he had a an apple right? they just come out on like Apple 2 or 100 or two. -. yeah.

so then he was measuring blood flow and stuff like that in the intensive care. but I managed my waiting list. You know there were hundreds of people with ulcers trying to get my new treatment antibiotics and so I had an answering machine, I had a push-button memory phone from Tandy and I had this S100 computer and and then I got a drug company like when I was one of my sponsors eventually to give me a copy of dBase - so oh, it's them writing had a database with debase and I was putting all kinds of information in there. and so all of a sudden I had 500 patients it being managed by the system together.

CPM Yep and so I write my first paper with Dr.. Warren they're on CPM and he calculated the statistics on his 11c Hewlett-packard calculator. Yep, the Voyager form factor. Yeah, yeah.

and then we published that. It was all great. and then eventually that led to the sponsorship traveling to the US. This is a tip: I'll tell you some secret stuff about the Nobel Prize Yes, please do so.

Just between us. So just between us. So in. America if you win a prize, you pay full tax on it.

Ah, in Australia it's techno exactly because. I prize by five. Yes. Okay, all right.

like out of kind of lucky, lucky for me I had not yet won the Nobel Prize and come back to Australia And then a few years later someone said Barry do you realize that if you've still got a green card, the US government can tax you from your global income? ah God it was I was like Julian Assange Yeah. So anyway so I went in and I snipped up my green card and filled out this form and gave it back to the US Embassy And then they said you're the only person we've ever heard of who handed in these green. There are other people that's great. So so anyway.

so I just started the business in Australia then and and I usually in these crazy bills from the US tech stuff to apartment they're really just trying I wonder it's like a really green card and then when we won the Nobel Prize of course no tax, excellent and most poor Americans they would be like getting half a million dollars. It's one point seven. I think it's one point seven million Kronor or something. Yeah, but effectively it's a million dollars U.s.

right? Something about. but you have to split it. Yeah, so Dr.. Warren I eight hundred thousand each U.s.

something like that. Alright, and you invite all your relatives to Sweden You know we'll travel around as crazy. Bus tours right? Go to the Opera and everything. Your family has a fabulous time because there's a big black tie dinner and they're waiting of Queens And it's pretty difficult because you've got shake hands with the king.

plus he gives you the middle. So which hand do you shake? This is a total stressful. yeah I'm sure it is so. but yeah, so this is your little tiny Nobel oh they give you that I don't carry the Nobel Prize with me tonight.

So I when I first saw it I said how come it's got a picture of Dr. Warren on it and they said no, that's Alfred Nobel hi Dr. Warren watches this I say Robin Warren Here you go wrong I gave you a good meat I'm sometimes carry some Nobel Prize chocolates. Anyway, so it's the Nobel Prize of physiology.

So in all medicine yeah, that's what it was called. better physiology or medicine in, you know, 1900. They weren't really sure of where one stopped in once done. So physiology means you know you might study the blood pressure of a cat, or you might put different drugs on you might get that artery out of a rat, you know and put it in a little thing that measures how strong it is or something.

You know that would be physiology one. What causes blood pressure or what causes, you know? Yes, Logical factors? Yeah, yeah, physiology is measurements. Okay, this one would be. You know you've got cochlea.

Yes in Australia But so they would know all about the physiology of the ear. if you said what's the resonant frequency of the eardrum they told you straight away. Yeah, because they've actually measured it. So that's physiology.

and or if I wanted to Dave if I wanted to train you how to keep your lab tidy. Alright, I would just like feed you every time you tidied it up. I've got yes, ever that would train you. Neurology? Yes, and medicine is more like human.

Okay, so in those days they didn't really actually Alfred Nobel probably had ulcers. He's into dynamite. Yes. Laurie He was a credibly rich tycoon and visited Australia selling dynamite to the gold mines and write everything and then.

But he used to sell nitroglycerin. That was his first business but it blew up. The East piece just blew up. but he used to try to convince people that it was safe and people all over the world were buying it and then getting killed.

Brilliant. And then one day the factory in Stockholm blew up and killed his brother. Oh, so he said maybe it's not safe after all. So he then mixed the nitroglycerin with some Montmorillonite clay, which is sort of powdery clay that's seen a lot of things.

It's it's like if it was cool, but it's just some of my white clay. plus some oil and some sawdust or whatever. And he ended up making dynamite which didn't blow up right because nitroglycerine is. Yeah, it's a liquid right? So unstable.

No, you get yes right? I'm gonna get D monetize some of your flavor videos getting a bit late glycerin and you mix a certain amount of you can look it up in ink. you look at mix it with sulfuric acid and then like you pour nitric acid into it and the reaction happens. It likes to be at body temperature alright and as you as it reacts it actually gets hotter. But once it's a hundred and months it's about 45 degrees centigrade to starting to become unstable.

So in Sweden during the winter you can make it and you take your off thermometer in there you know it's only 42 and put a bit more. you know I'm in a bit of a hurry today and it would heat up too much. Oh I see so you can imagine what happened. Yeah, so it might actually be the beginning of the Swedish tradition of everything being safe.

like Volvo cars. you know is where it's safe right? We remember what it is. we can't get safe, make it safe. So maybe that was part of it.

Anyway, so he gave his so he always had a gut ache. Stomach ulcers. We don't know that stomach ulcers cuz the only way they could diagnose it is when you died. They did post-mortem on stomach ulcer, not stress after all you know.

So, but the treatment. Before our discovery, the treatment of ulcers was the treatment for stress. Dave Yep, you'll have to give up this all your you know 10 subscribers. They're gonna be brokenhearted but but you've just got to give it up.

You've got to retire. Yeah, just go and live on the beach and like fix fix car radios or something like that. I'm there so that would. So I Met people like that who had a fabulous, interesting career and they just retired at age 50 or something and they still had ulcers.

Yes, so this stress thing was just totally bogus. So the treatment would be. They would tell you you're not allowed to eat any spicy food nor that grapefruit juice or citrus. Okay, you're not allowed to have fish and chips.

You've got to have just boiled steamed everything with a lot of cream in them and that would be what you lived on. Yeah, and you could never drink white wine or red wine or anything or too much beer. Your whole life was miserable and and you still have no else's problems, right? So then and when do you reckon you died from I Don't know. Atherosclerosis.

You hate so much, so much oily fat and everything your cholesterol would be ten times no more. Your blood a full of lipid and so poor. Alfred Nobel Eventually started getting angina and he was I don't know, it's about eight years I think and he eventually died from a heart attack and he had no friends because it was lift money to prizes. So we're going back.

What are they? So the answer is first Monday in October Every year they announced the first Nobel Prize which is medicine. Okay so whatever the date isn't much use. about the 3rd of October they're about. so that was my date and then after the next morning they did physics and after that chemistry.

all right. and then they do literature and then they do Peace Prize Yes and that's the one that gets the publicity because that is actually well does my that is announced because when Sweden separated from Norway about a hundred years ago they said to the Norwegians you guys can do the Peace Prize so that's announced in interesting in Norway Oh okay okay they get to meet the king of like we know yeah you made so good. The favorite ones is actually the Swedish ones right? The Norwegian one is usually right. Is it gonna be Bob Geldof or is it somebody else you know.

But if someone said to me what about Obama because there's no way that he could have got his application in on time by the rules and yet he's still won the place to do so I Thought about it for a while and I said well the peace price is usually pretty controversial controversial when I look back through the people I know got the Peace Prize like terrorists when I look back along the what I know that the Peace Prizes in the last 30 or 40 years Obama was one of the best difficult in teresting. All right. So then there's another one that's called the commerce price which is the bank of Sweden in honor of no gold something but sort of it. okay, proxy one or something and that comes on and it's pretty interesting God where does the money come from these days? Cuz sure there's money I know it.

So what he did. he left all his money for the Nobel Prizes which was sixty million dollars in today's money I think okay and you said the so they spend the interest on the money on the prize each year and and keep it going. so oh, that's probably built up to hundreds of millions. Oh okay, so it's just the interest on the money was a notice like a million dollars Yeah but the really good prizes like the Nobel the reason it's good is because they get top professors and scientific people or and authors and everything all over the world and all the previous Nobel Prize winners get a nomination slip each year in the mail.

Also you can nominate this so I told my my my the only people who can dominate well you know I'd like to see Vice Chancellor of the University of Sydney right? And they're my are sir. gas nozzle from Walter and Eliza Hall Institute he might have but he was. He might have had a mate on the committee. Okay, you know somebody like that.

So people of no trusted people in science get a nomination form and Mayall send them in so they come in like votes. Is it? They don't know, They know they know it's from. Okay, so you actually don't. You know you don't get an ordination certificate the only few photocopier day I'll tell it's not real.

Okay so I told my mum all those letters she wrote to them right? they probably just got shredded. Yeah, I'm sure they get done. That's right, they do. Yeah and it's And the thing is, it's like what happens in Las Vegas when you think you might be a Nobel Prize winner you and you can never mention the Nobel Prize and there's someone says Barry do you think you will ever win the Nobel Prize Definitely jinx you.

So who are you up against? So so what happens is they get hundreds of votes probably from these people and so they get a shortlist say professors all over the world. A lot of met and respected people say this would be a good one for medicine and and then and then so nothing happens for years and years and then finally probably someone on the Nobel Prize Committee gets and also oh Sandy boy Wow that is great. So we it was nominated years before so and so people used to sort of mention it in that and so about 95 it started to be big in medicine plus documentaries and things like that. and the link with stomach cancer was important because in a lot of places like Japan and China that was the most common cancer.

Oh yeah like in China Even today 300,000 people here died from stomach cancer Wow because the property cause of this germ. So then so cantering popular. After about 95 96 and I had a medical company and you know there's all kinds of hype going on about it and then soon after that we figured out really good treatments forth which one became available in Australia about 1998-99 and then all the doctors in Australia really embraced the whole thing about. you know it, crazy they just treated anyway you ever mentioned the word Elsa they just gave either any side effects if you don't have it and you get there and you take this oh yeah all anybody's you could be allergic.

oh you could. Do you know this stuff about your microbiome? Oh and all the gas. You're into things like that so they can't upset your guts in different ways but usually it bounces back because if you if you lose if you so I don't want people to stop taking antibiotics if you if I need them they're the best things ever. But they do kind of wipe out the gut bacteria temporarily usually.

but in your family, you'll soon catch the germs back up. of course your partner of the kids you know of your old toothbrush, you know. Yep, you've got those germs around in your environment. You can go out and take probiotics so he'd do it or whatever.

You could get them back so that's what we notice. but that's that's a hot new thing now, right? So you wouldn't want to take antibiotics in this year. the antibiotic thing nowadays they're talking about bacterial antibiotic resistant bacteria. Are we? Because people aren't doing the full course and how big a problem? So the treatment would give H Pylori Helicobacter Helico means twisty bacteria, so corkscrew-shaped bacteria.

Oh okay, it's physically show you pretty easy, right? You can see that under the microscope Kenya Yeah and actually if you type out bacteria at Google search images Helicobacter you get about 50 pages of brilliant Oh I actually want us Came third or something in an animation about five years ago or ten years ago I Paid for it myself and got a graduate animation student out of Kyoto Sydney who did it on a beach in Thailand So you take so if you get diagnosed as having it so the doctor does a breath test or a blood test or maybe you had the scope down and the oyster and rather just found it, you would take a treatment of antibiotics plus acid lowering drugs. okay, acid blockers so it's usually three drugs tripled there. Why? Why do you have to lower the acid level? Well, the antibiotics are designed to get into your lungs or your urine. That's it.

OPH All right. Oh yeah. So yeah, if you put antibiotics into acid, they don't work right. Got a bunch of they're like giving him road signs if you're walking towards the antibiotics.

But if you get rid of all the acid out of the stomach, that's the key thing. Then ordinary antibiotics like amoxicillin start to work and so we can cure you in 10 days 1014 days. It's an end of story. You just don't have it.

You're also slightly cured fantast and you would be very, very unlikely to have any long-term effects like stomach cancer or anything like that. So into surfing. So all the GPS just wiped out all the H pylori Helicobacter and ulcers in Australia fantast. and so now we don't worry about people still dying from ulcers.

Dainius This is like a there's a lot of people in the world. Yeah. and of course the the diagnosis and treatment probably cost hundred fifty dollars if you ride it all out. So that's a lot of money for developing nations.

Yeah yeah, so the things we've been doing in developing nations is going to make a difference. Like in India they're cleaning up the water yes everybody toilets. So basically you've got the basic for us. You know water comes in, they're clean and the pool goes into it then goes out the other side.

That's the that's the first discovery that save more millions of lives than anything. it was yeah actually the invention of the flushing toilet they say you know and who was the inventor? What was his name? Mr. Crapper was the flushing toilet. So the water used to come from the mountain by Ecuador the toilet set on what I was probably in business class.

So anyway, how did you find out about you Nobel Prize I was a shot. so you were nominated. So this is one of these stories you never allowed to meet. you know, right? Okay, so never won now allowed to mention you've been nominated.

That's right, I want you right. They can really take it back even if you were lying. Got it? So so Dr. Warren he's the pathologist he retired Missy and I was traveling around giving lectures and talking about my pup.

Bought my book and everything and I never used to seem very much and so I said look Robin why don't I pick you up on Nobel Prize night and we'll go down the pub and and then we'll listen to the announcements. You know you never know we've met I mean I Live streamed ever watch the live stream anyway? So right. Yeah yeah. so we didn't have live streaming.

we had a Nokia 911 us right? So I said to my wife I'm going or no answer so I started this and I said afterwards. We had a lot of fun reminiscing and we usually gets a big pint of Guinness I just have a Mew export in our fish and chips there and we go to the Swan Brewery Pub. it's on the on the Swan River Yes now this the pub you know I get rich people live there not me and so we would. We did that and at the end of it Isis there was about year 2000 because we thought I said you know I think it's building up someone said I got him wider to give a lecture this year in Sweden yeah so anyway they announced that it wasn't us so the following year I did the same thing.

picked up Robin at 4 o'clock and the announcement of the Nobel price is at 5:00 5:30 p.m. in Perth So for 4 p.m. I pick him up and take him to the brewery and we'd sit down and chat on and I have our fish and chips and Guinness and everything. No so that year we'd boy no no no I know I know it's now two years since I've given the lecture in Surrey and we'd had a conference about it a couple years before and we missed the boat you know and they've gone on to say something that I couldn't understand and and so then we were there at the at the pub and I'd gone to the problem I said to my wife come on come see Robin we're going to the pub and we'll listen to the announcement and she says I know no I'm too busy I can't do I got to prepare lunches and she's thinking oh he's not gonna win no that was the lowest priority in her mind and she was cooking cabbage or something.

She's actually got more degrees than me so I shouldn't All right? So anyway so I'm me and then Robin Warren's phone rings at five o'clock and he says hard and they said hello Dr. Oren is that Dr. Oren I'm Hans your vowels that the head secretary of this the Karolinska Nobel Committee and you and Dr. Marshall have won the Nobel Prize you know so it was the right time you being how long before the announcement like half an hour before half an hour be from so he he said well he's pretty did peace oh that's very nice thank you and they said but but but won't we got a problem.

We're not allowed to announce it until we've spoken to you and Dr.. Marshall yeah and we can't find him anywhere. We've called his office, they don't know where he is. He recalled his home and called this and that and he's not in picking up his mobile.

we don't know where he is. He said oh well he's here right? Mate with me. we're at the pub they meet. they said late bloomer speak to Dr.

Marshall he's on hand the phone over. Yeah so Dr. Marshall you've also won the Nobel Prize with Dr.. Wharram and I said are great and so I hung up.

So then I called my wife I see I said you got to come here to the pub this special I want to tell you and she says are no no no no no I've got the potatoes on and then at that point she looks down on the table and there's my wallet and she says that swine he's just calling me because he's lifting so I'll come. So then she came in and we told us though it's pretty exciting then. But then the one thing when we got to Sweden that Dr. Hulme Val's the head of the Nobel Committee you know I'm very very worried because the Nobel Prize is so secret.

They plan all year and they have this final vote but some hours before the announcement. oh really just any better. you know it's like a not guilty or guilty. Another jury comes yeah and then somebody comes out reads the announcement.

the winner is blah blah blah yeah and they actually have somebody prepare several websites in all of them. is they had their shortlist, you know? and then they have like ten bites around the table on the day, right? They must have an uneven number mus and they otherwise they could get a toy. Yes they must anyway anyway so he was really worried. He said since the Nobel Prizes so secret, how come you and Dr.

Warren were already down the pub cellar right? Everyone else? of course we're Australian mate. that's what we're just about. But but seriously, they scan that room. they don't want anyone.

yeah listening to their discussions right? So there's only event. All right. You actually get yes game. There is a website, he's probably in the room and the committee A and then and then they come out and they switch on one of their little websites.

There's a couple of pages about it. Yep, and it's done. Wow so I guess pretty exciting. Awesome.

Luckily we know that's we're getting on the booze anyway. most press Swedes I'm pretty frightened about that's terrific and so now so finally both. Final thing is you have to give a speech at this yesterday. New 8,000 baby, 1,500 people and you can thank your mama.

Yeah yeah but you have to give a little speech. So yeah I found out this would MacFarlane Burnet one of the Australian Nobel Prize winners from Melbourne Famous right he they go invented like mix mitosis or something. plus because first thing is rabbit killing virus. okay but when they invented the myxomatosis and started getting released in Victoria for the rabbits right people had a had a epidemic that some of encephalitis a whole Murray Valley encephalitis or something in my opinion they're coming down with it.

Was it linked or was it that just echoing everyone else That question? Yeah. so MacFarlane booth? yeah and he's two mates names escape me right? No drape the virus to prove that it was almost a human's right. and they won the Nobel Prize but not for that the guts to discover the important white cells in her community and things like that vaccines. So that was just because I mean I were Australian just we.

Yeah, we've got this tradition of drinking our own bacteria which is one of the things I did that was also famous. Oh okay okay just got this tradition. It's not really a guarantee that you're gonna win the Nobel Prize I don't want you Aussie doctors out be experimenting on yourself. Yeah so that was one thing in there and they and then finally to make sure you're gonna win the prizes.

This is what I recommend to all your young scientist is work hard yes, keep balance in your life. yep and just in case, always be kind to Swedish P So why do you do you think you're one your idea? Got it? Because it was it overturned centuries? Yes nice of Dogma right. It turned that 120 page also chapter in the Medical down to six or something, right? It's a germ. Take antibiotics in your story.

Ten percent of the population in the Western world used to get an ulcer. so like 'hey you could have come down with an ulcer and you know, forty years ago and I've told you it was stress. Yeah and you could have had surgery to cut out half your stomach. Yes, too much.

I will have surgery that kind of stuff. You know it was a life-changing disease. Yeah, you could have given up all this year. I Mean you might have had to sell your whole lab for like 20 bucks or Gumtree exactly my dodgy old science.

I Always actually very serious. And people the essent acid blocking treatment people used to take called Zantac and Tagamet with a too big drug right? They were like 5 billion dollar drugs for the drug companies and that was wiped out. Well he, no, no, they were smarter. they figured out how to sell it anyway.

you get it in the supermarket. Okay, everyone gets indigestion from ass. Ok so it does something else new remarketing, but so it it'll keep your acid and your also under control. But when you stop taking it if you run out a week later, you get your also back and you could hemorrhage or something.

you know. So that was the thing. I See so that used to cost people in Australia about 5 bucks a day in more to watch. You don't want those newfangled watches Jesus yeah, it's Tim Cook watch.

Oh yeah, one of those Apple II think my flavored ones. Mine's supposed to take an ECG but they haven't got it enabled in Australia yet because it's not legal to do medical tests on yourself with you. Really? Is that why only in America So far, only in America There you go and America so else's story. Yep, ten percent of people in the Western world used to get ulcers and about 50% of people and on the earth had the bacteria and would say House get your Montana vomiting attack Some people say I can't eat pizza I can't eat bread, drink red wine.

that kind of stuff. So when we discovered this, it really benefited maybe a bit. Ultimately, a billion people. Your people.

Yeah! So in China now I visit China is half the people have got it if you average them out, but in Shanghai and those wealthy parts of China it's like Australia much less. You know we will probably through our North Marshall centers and treatment recommendations and things, but we will probably indirectly influence a hundred million or two hundred million Chinese people will take now. That's fantastic. So you will find some I Might you'll find me in a couple of other youtube search talking about.

Also, try and find Emily Thank you very much Peridot! Thank you for teaching me about electronics sometimes I Need something? Yeah, we'd love to. We could spoil spend the next two hours talking about vintage tech gear and you've got like your you notice that famous oscilloscope you said you got I got a 2465, be down Yes Phyllis Cope and you're going to visit the vintage tech museums? Yeah, yes, so it's in Boulder Colorado I think so. Got a few connections there and I have a couple of days conferencing in America mm-hmm And if I can get a couple of days off at the end of it or go somewhere nerdy like that either there or NASA Space Center Fantastic Yeah, should be jealous. Alright, thanks Barry for joining us.

Yeah off the cuffs. Thought we'd turn the camera. hope you liked it next time. I'll bring the middle Yes please.

Should I need something to drill a hole in this open door? like it presumably it opens every nor Nobel Prize they they say they are you getting one So it got me into the Shanghai World Fair Oh okay and so we came. We turned up at the pavilion there the Aussie pavilion or the Chinese pavilion and there was this big queue of them. The main queue was had people long so we we saw someone going around through this back door. We came in and we said can we get in there and they said it was me and my mate Peter Hammond from Sydney Ashley yeah and we said what's that door for and they said oh that's the VIP door and they said have you got your VIP pass and I said oh no but I got my Nobel Prize medal is that good enough Went down the middle and they like perfect.

Yep you guys well son doesn't have brilliant brilliant Okay thanks better guys I dip as aw yeah no worries we're in Australia Yeah yeah I'm from Calgary is aa gold mining town is a goatee ironic isn't it that you know? Yeah that thing got the gold and there were all migrants there. Yeah and I always to get ulcers. Hey not anymore. ya know what's in the story? All right Thanks Buzzer Okay catch you next time.